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Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and b-amyloid peptides

Common side effects are gastrointestinal (nausea, vomiting, diarrhea, constipation), particularly during dose escalation

a disclosed composition may comprise a peptide copper complex derivative that is a derivative of GHK-Cu having the general formula: GHK-Cu copper(ll) where R is an alkyl moiety containing from 1 to 18 carbon atoms, an aryl moiety containing from 6 to 12 carbon atoms, an arylalkyl moiety, an alkoxy moiety containing from 1 to 12 carbon atoms, or an aryloxy moiety containing from 6 to 12 carbon atoms

Ando 2015)