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Vice versa, direct occlusion of the superior mesenteric vessels, vein, artery, or vein and artery (i.e., portal, caval hypertension, aortal hypotension, peripheral lesions) rapidly induced the intracranial (superior sagittal sinus) hypertension, brain swelling, and lesions [14,15,16]

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5.3 Gut microbiota characteristics in comorbid states 5.3.1 Synergistic alterations It must be explicitly acknowledged that the synergistic alterations described in this section are largely inferred by overlaying independent findings from constipation-only and depression-only cohorts

Thymosin alpha-1: the most clinically studied Thymosin alpha-1 (TA1) is a 28-amino-acid peptide that modulates the immune system, supporting T-cell function and helping regulate inflammatory responses