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Vitamin B12 is a water-soluble vitamin essential for red blood cell formation, neurological function, and DNA synthesis Requirements vary by age: infants need 0.30.4 mcg daily, children 0.51.2 mcg, and lactating women 2.0 mcg Pernicious anaemia typically requires intramuscular injections of 1,000 mcg hydroxocobalamin, initially three times weekly then every 23 months Deficiency causes macrocytic anaemia and neurological symptoms including paraesthesia, balance problems, and cognitive changes that may become irreversible B12 is found almost exclusively in animal products