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Methylation reactions are critical for numerous metabolic processes, including the synthesis of choline and the detoxification pathways in the liver

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It has been indicated that prolonged administration of MSG (4 mg/g) significantly induces apoptosis in a time- dependent manner in the rats thymocyte cells via disturbing the fine balances between prooxidant-antioxidant system, with excessive production of ROS and resulting oxidative stress status [46]