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In multiple neurodegenerative disease models, lipid-based nanoparticles, polymeric systems, vesicular carriers, and dendritic platforms consistently enhance brain accumulation and neuroprotective efficacy when rationally designed

DIAGNOSTIC CRITERIA FOR VITAMIN B12 DEFICIENCY USED IN STUDIES ASSESSING THE VITAMIN B12 STATUS IN PATIENTS WITH T2D ON METFORMIN THERAPY Despite the diagnostic specificities of vitamin B12 deficiency and the necessity to measure biomarkers without suggestive symptoms, most studies assessing the risk of vitamin B12 deficiency in metformintreated patients rely solely on total vitamin B12 levels to confirm the diagnosis

81502582) and the Fundamental Research Funds for the Central Universities (N182004002)

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