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Description

Under pathological conditions, they may initially exert neuroprotective effects, yet prolonged activation often results in metabolic disturbances and neurotoxic gliotransmission, highlighting their dual role in CNS pathology and their potential in therapy [293]

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TABLE 2 Summary of phytomolecules with neuroprotective potential in Parkinsons disease

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An integrative mRNA analysis revealed that EMT-related genes, such as IL-6 , are upregulated in sunitinib-resistant RCC, indicating roles in mediating tumor cell resistance ( In addition, the TME drives EMT by providing cytokine and ECM signals that promote a mesenchymal, invasive phenotype (Figure 3)

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10.1080/15548627.2017.1381804 Autophagy

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