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Reducing RIPK3 expression or inhibiting its activity significantly reversed the elevation of cleaved caspase-3 and proapoptotic protein Bax, thereby ameliorating AKI

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6 Key Takeaway

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Overall, RIPC is a potential mitochondria-targeted strategy for protecting the heart and kidneys from ischemia-reperfusion injury, and may be more valuable for patients with prolonged ischemia

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Loggers were programmed to take temperature readings every 30 min

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