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Finally, the types, locations, and stages of brain tumors, as well as the therapeutic regimen are also important factors to be considered to hypothesize the desired effect (pro/antioxidant) from an exogenous antioxidant in brain cancer treatment

In summary, the core of the nicotine rewarding mechanism lies in its profound impact on dopaminergic transmission in the mesolimbic system, achieved through complex direct and indirect pathways

Collectively, these results demonstrate that deletion of Keap1 (and subsequent NRF2 hyperactivation) drives CD8 + T cells toward dysfunction, marked by reduced expansion, diminished effector function and acquisition of a T tex phenotype

Weston CR, Davis RJ (2007) The JNK signal transduction pathway