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doi: 10.3390/cells11162472 238 MaZChenWLiuYYuLMaoXGuoXet al

Finally, equine hepcidin, an antimicrobial peptide also involved in iron homeostasis, was discovered and analyzed concerning its tissue distribution

Further research is needed to elucidate the basic mechanism underpinning T and B-cell recruitment into an immune response, to examine antibody affinity maturation and to identify the determinants of the immunodominance hierarchy for T and B-cell epitopes, which ultimately may enable vaccine antigens to be rationally designed to induce broadly targeted immunity