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For musculoskeletal indications, most patients at our Doral clinic report a noticeable reduction in pain within 2 to 3 weeks and a functional improvement (range of motion, strength, load tolerance) by weeks 4 to 8

[277] Under policies finalized in the CY 2023 PFS final rule, the 18-month exclusion period for Leqembi would begin on April 1, 2023, which marks the first day of the calendar quarter after the drug's first date of sale as reported to CMS in January 2023

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