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Receptor associated protein (LRPAP1) for newly synthesized LRP1, which also functions as an antagonist by interfering with the binding of this receptor to its multitude of ligands and may affect receptor folding (Marakasova et al., 2021)

After crossing external barriers (seed coat, root surface, leaf cuticle), putrescine, spermidine, and spermine are taken up across the plasma membrane via specific polyamine uptake transporters (PUT family and related carriers), whose roles are now documented in Arabidopsis and crop species 78,79

The large pre-protein is later cleaved by cellular and viral proteases into the 10 smaller proteins that allow viral replication within the host cell, or assemble into the mature viral particles

It further explores how integrating both approaches can support a more comprehensive and clinically meaningful evaluation of interventions including advanced wound care technologies by capturing both controlled efficacy and real-world performance