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Vitamin B12 is water-soluble, meaning excess amounts are excreted in urine

doi: 10.1016/j.addr.2008.09.001 19 AnFFZhangXH

Ethoxyresorufin O-deethylase and methoxyresorufin O-demethylase activities were measured in the same way as described for the pentoxyresorufin assay, except that the concentration of substrates was 1.7 mM ethoxyresorufin and 5 mM methoxyresorufin assays were carried out using the microsomal fraction of the tissue ( 2.22 Statistical analysis Data were evaluated by ShapiroWilk tests to confirm normality of distribution and by Grubbs test to identify outliers

Finally, a glutamine-enriched diet is also shown to increase the abundance of beneficial Bifidobacteria in the jejunum of healthy weaned mice (194), and to decrease potentially harmful microorganisms in adult pigs (196)