methylglyoxal glutathione reductase Model illustrating the metabolism and detoxification redox assays Research area Frontiers | Methylglyoxal, the dark

Simulations suggest that glutathione pools are most sensitive to exposure duration at pharmacologically and supra-pharmacologically relevant doxorubicin concentrations

Owing to the velocity of blood movement through the voxel, MRS does not detect GSH signal from blood, thus, the measured GSH values reflect only GSH in brain parenchyma or CSF

GST loses its ability to bind Glutathione-Superflow Resin when denatured, and consequently strong denaturants such as guanidine-HCl or urea must not be used in the purification buffers

Structure-activity-relationships of isothiocyanates as mechanism-based inhibitors of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in A/J mice