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demonstrated that HGF could decrease the acute phase of the inflammatory response by attenuating the production of IL-6, and increasing IL-10 levels, in lipopolysaccharide (LPS) stimulated bone marrow derived macrophages ( db/db mice to study diabetic nephropathy, demonstrated that when the HGF gene was delivered to these animals, there was a reduction in the circulating levels of IL-6 and MCP-1, an increase in the number of M2 macrophages and an improvement in glomeruli inflammation ( Two studies from the Morishita group ( in vitro study and an in vivo study

Two-sample t tests were used to compare continuous baseline characteristics

Instability is also more common in cases involving abnormal curving of the spine (spondylolisthesis) and fluid-filled sacs in the spine (facet cysts)