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The group that deserves the most caution Based on the case literature and the thyroid mechanism described earlier, the highest-risk group appears to be people with pre-existing thyroid disorders

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Notably, while complex I assembly and mitochondrial mass remained unchanged, we observed significant upregulation of pan-Kla (lysine lactylation) on the complex I subunit NDUFS1 (Fig

Detailed analysis of the collected data was performed, allowing behavioural domains where treatment demonstrated a particularly notable improvement to be identified