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This process involves adding and subtracting electrons for the purposes of oxidation, reduction, hydrolysis, hydration, and dehalogenation to change around these compounds and prepare them for phase II liver detoxification

Advantages of these methods are that no matrix or matrix matched calibration or expensive stable isotope-labelled standards are required

Anita Skrtic, [email protected] This article was submitted to Translational Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Blocking inhibition, for example, replicates symptoms resembling those observed in neuropathic pain patients 2