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Binding of apoptosis-linked gene-2-interacting protein X to its N-terminal region promotes secretion, whereas keratin 20 binding at this region inhibits secretion and thereby prevents ferroptosis in kidney tubular cells [152]

Aluminum - Aluminum exposure can occur through ingestion of processed foods with aluminum additives, drinking from aluminum cans, using personal care products like antiperspirants, and smoking, which can release aluminum particles into the body

183,184 IL-4 and IL-13 induce STAT6 in target cells with JAK involvement, and gene-targeted knockout mouse assays revealed STAT6 contributes to IgE synthesis, bronchial hyperresponsiveness and airway remodeling upon allergen sensitization

Gilberts syndrome is commonly associated with a defect in the promotor region of exon 1