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doi: 10.1016/j.annonc.2023.02.011 268 HuangJLiuDWangYLiuLLiJYuanJet al

The key events (KE) identified include the MIE PPAR activation measured as a characteristic change in gene expression, KE2 increased enzyme activation, characteristically those involved in lipid metabolism and cell cycle control, KE3 increased cell proliferation, KE4 selective clonal expansion of preneoplastic foci, and the AO increases in hepatocellular adenomas and carcinomas

Stigmasterol alleviates interleukin-1beta-induced chondrocyte injury by down-regulatingsterol regulatory element binding transcription factor 2 to regulateferroptosis

Dose-response relationships between individual nonaspirin nonsteroidal anti-inflammatory drugs (NANSAIDs) and serious upper gastrointestinal bleeding: a meta-analysis based on individual patient data