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Notably, all patients had previously been treated with pentosan polysulfate, which is currently the only FDA approved treatment for interstitial cystitis, and had not responded

Unlike the cheap synthetic folic acid you find in many supplements (a totally man-made chemical that works very poorly in a significant portion of the populace), methylfolate benefits every cell in the body because its in a bioidentical form

Other contributing factors include an inefficient diagnostic system, a lack of public awareness and oral hygiene, inadequate healthcare facilities, and limited access to medical resources 1,10,11,12