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Always follow your clinicians specific instructions

The systematic review protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO), registration number: CRD42024554513 (Available from) ( 2.2 PICOs question The primary research question addressed in this review was: What is the effectiveness of sublingual/oral administration of Vitamin B12 alone or compared to other forms of administration (e.g., intramuscular injection)?

Proper technique involves cleaning the injection site with alcohol, pinching the skin to create a fold, inserting the needle at a 45-90 degree angle, injecting slowly, and rotating injection sites to prevent irritation

While intravenous or intraperitoneal routes may improve bioavailability, they are difficult to apply in small animal models