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Ganetespib acts as a radiosensitizer in pancreatic ductal adenocarcinoma by disrupting HIF-1, STAT3, and AKT signaling and inducing G2-M cell cycle arrest, thereby impairing DNA damage repair during irradiation

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This increased lifespan correlated with a decreased incidence of lymphomas and reduced glomerulonephritis

The most effective concentration of HGF (10 ng/ml) was subsequently found to stimulate hippocampal neurons in organotypic hippocampal slice cultures which are more intact preparations similar to Dihexa (FIGS