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Signal 21 , 52 (2023)

HBsAg seroclearance further reduces hepatocellular carcinoma risk after complete viral suppression with nucleos(t)ide analogues

This action is achieved by blocking the PI3K/AKT pathway (166)

This activation triggers the early upregulation of CD69, a crucial factor for retaining naive T cells in the lymph node to facilitate continued activation (70)