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Energy is produced at each stage of the process, and stepwise shortening of acyl-CoA generates one molecule of FADH 2 and NADH for every two-carbon unit released, while each acetyl-CoA molecule yields 3 molecules of NADH, 1 molecule of FADH 2 and 1 of GTP via the tricarboxylic acid cycle

In response to Cd toxicity, GSH primarily acts as an antioxidant that is associated with detoxifying ROS, but it also plays a critical secondary role as a redox buffer (Zhang et al., 2013)

Some anticancer agents, such as xenobiotics and radiation, act by producing ROS to kill tumor cells

Some patients achieved disease stabilization and one lymphoma patient had a partial response (285, 299, 300)