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Accordingly, glutamine metabolism plays a role in gene expression through the contribution of -ketoglutarate and succinate to chromatin structure modification

Treatment of mouse colonic epithelial cells with butyrate stimulated expression of N-acetylglucosamine 6-O-sulfotransferase-2 (GlcNAc6ST-2), an essential enzyme for the synthesis of sulfomucins (Tobisawa et al