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Muscle Nerve 2004

393 Karow et al

Feeling run down doesn't have to be your normal

revealed that CDKN2A deletion reshaped the lipidome of GBM, redistributing oxidative PUFAs to distinct lipid compartments, thereby increasing lipid peroxidation levels and significantly increasing sensitivity to ferroptosis ( in vivo ( 2.3 Imbalance of the antioxidant defense system The occurrence of ferroptosis in GBM cells not only depends on the activation of death signaling but is also closely related to the functional imbalance of the endogenous antioxidant defense system