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Notably, in addition to trying to block potential downstream detrimental effects, new therapies need to be designed that preserve and boost astrocytic defences and improve astrocytic homoeostasis

It is hydroxylated into the catechol estrogens 2-hydroxyestradiol and 4-hydroxyestradiol and into estriol (16-hydroxyestradiol), reactions which are catalyzed by cytochrome P450 enzymes predominantly in the liver, but also in various other tissues

Having a psychologist on board for weekly sessions is not only suggested but necessary

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