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Manipulation of dietary carbohydrates can alter 1,5-AG levels, with reducing glycemic index and limiting carbohydrate intake having the greatest effect

2.2 Expression and regulatory mechanisms of key molecules in neuronal metabolism While Pfkfb3 expression is comparable between neurons and astrocytes, there is a significant difference in the degradation process within neurons

10.1046/j.1469-8137.2003.00813.x 65 HallJ

In addition to causing constant cellular injury, chronic inflammation creates a microenvironment very similar to that of cancers, which favors the establishment, infiltration, and growth of neoplasms (102)