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WHO recommends screening for G6PD activity of all infants in countries with high prevalence of this deficiency

It is the most abundant thiol-containing antioxidant in the human body and exists in both a reduced and oxidized state in cells, with over 95% of GSH existing in its reduced state [1]

32,88 A quantitative flux analysis showed that the direct contribution of ME to NADPH generation was estimated to equal the contribution of the PPP

confirmed that the up-regulation of Drp1 induced by high glucose promoted the release of hexokinase-II from mitochondria, which subsequently inhibited the PINK1/Parkin pathway of mitophagy, leading to retinal damage in DR