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Ele compara esse fenmeno ao dos esteroides anabolizantes

Although the release of these proteins into the cytosol is expected to trigger apoptosis, this form of cell death is negligible in APAP-induced hepatotoxicity, as shown by the absence of caspases activation and the inability of caspase inhibitors to protect against APAP-induced liver injury ( in vitro after treatment with APAP and fructose, which acts as a glycolytic substrate to generate ATP and glycine as a membrane stabilizer (Kon et al., 2004)

Description of statistical methods The final analysis considered all recipients of normothermically-perfused kidneys