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More specifically, the prominent role of Nrf2 pathway in oxidative stress handling throughout life is further emphasized by the fact that the inhibition of this pathway by progerin has been incriminated in the premature aging occurring during progeria disease (Silva-Palacios et al., 2016)

Long-term human safety has not been fully established

If not addressed, these toxins can build up and cause a long list of issues

Highest concentrations were determined for caffeic acid, besides ferulic acid, catechin, 5-(3,4-dihydroxyphenyl)--valerolactone, and taxifolin (Table 2)