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Oxytocin in Perimenopause: Beyond the Bonding Hormone Oxytocin is a natural peptide often called the bonding hormone because it supports trust, closeness, and emotional connection

FDA nonclinical toxicology review (2023-2024) flagged DNA damage in pituitary cells and injection-site necrosis in animal studies, plus immunogenicity and impurity risks from compounded material, alongside GH/IGF-1-axis effects such as fluid retention, joint discomfort, flushing, and headache reported by users

Mild side effects, like redness or discomfort at the injection site, or temporary changes in mood or sleep, are usually short-lived

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