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It is important to emphasise that these proposals are based almost entirely on preclinical data principally in vitro (cell culture) experiments and animal studies and have not been reliably demonstrated in robust human clinical trials: Stimulation of follicle enlargement: Laboratory studies suggest GHK-Cu may increase hair follicle size, potentially counteracting the miniaturisation associated with androgenetic alopecia (pattern hair loss), though this has not been confirmed in humans

Harmonized definitions for immunologic outcomesintratumoral CD8^+ T-cell density, dendritic-cell activation markers and myeloid suppression indicestogether with uniform safety reporting will enable comparability across studies and accelerate iteration of severity-based management algorithms, an approach that has improved clinical translation in adjacent cellular-therapy fields