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Description

The discrimination among the substrates almost exclusively favor 5-AD for HsaGST A3-3 and EcaGST A3-3, whereas trans -2-nonenal is a signature substrate for HsaGST A4-4

PLoS ONE 9 , e94209 (2014)

This study further supports that this local destabilization is dependent on the nature of a non-polar branched or medium-long aliphatic amino acid side chain