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3 Ferroptosis: characteristics and molecular mechanisms In recent years, ferroptosis, a newly identified form of regulated cell death, has emerged as a distinct mechanism characterized by iron-dependent lipid peroxidation and morphologically distinct from other modes of cell death ( + mediates Fenton reactions that generate hydroxyl radicalshighly reactive species that oxidize polyunsaturated fatty acids (PUFAs) in phospholipids

Nur E, et al