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Because the treatment delivers nutrients directly into the bloodstream, absorption is far more complete than anything a cream can achieve through the skin barrier, which translates to more even brightening from within

Rare risks include copper toxicity, particularly in individuals with underlying conditions such as Wilsons disease (a genetic disorder causing copper accumulation), and theoretical concerns regarding angiogenesis promotion in the context of active cancers

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Cosmetic formulations, however, may use other copper complexes, different carriers, and much lower concentrations