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Description

Stareini, P

Several promising compounds have failed in clinical trials due to a range of challenges, including inadequate disease models, late intervention timing, insufficient biomarker validation, and difficulty in distinguishing symptomatic from neuroprotective effects

Available online at: August 9, 2024)

A stable structure that binding to HER2 proteins inhibits HER2 degradation, leading to sustained activation of the PI3K-AKT and RAS-MAPK signaling pathways, which contribute to BRCA progression 33