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Among these, the study of its anti-inflammatory effects has become a particularly interesting topic, especially in rheumatoid arthritis (RA)

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Oxidative stress results from a disturbance in reactive oxygen species (ROS, such as singlet oxygen, hydrogen peroxide, hydroxyl radicals, and superoxide) production and/or degradation leading to an oxidant-antioxidant imbalance, and accompanies the primary mechanical impact in the TBI model

13,14 In contrast, although our study showed that patients who had immune-related adverse events received a significantly higher median number of checkpoint inhibitor doses compared with patients without such adverse events, the number of checkpoint inhibitor doses received did not significantly predict the occurrence of immune-related adverse events