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PHARMACOKINETICS: Absorption Following a subcutaneous injection of single dose of 4 mg Somatotropin in healthy male and female adults, the extent of absorption (AUC) was 291 hr.g/L and the peak concentration (Cmax) was 37 g/L

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Functional enrichment analysis showed that MOTS-c improved angiogenesis, inflammation and apoptosis in terms of cell function, suggesting that MOTS-c may have the same effect as aerobic exercise and improve heart failure in patients with diabetes through NRG1-ErbB4 pathway (14)