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doi: 10.1146/annurev-immunol-032713-120236 95 YangLZhengYMiaoY-MYanW-XGengY-ZDaiYet al

Although TNF at this dose exerted no cytotoxic effects, H 2 O 2 pretreatment resulted in marked cell death in both HepG2 cells and NCTC1469 cells in response to TNF challenge (Fig