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This produces an inactive residue that is proposed to be harmlessly cleared from the blood

5.2.2 Sorbitol Metabolism and Aldose Reductase During normoglycemia, glucose entering the cell is rapidly phosphorylated by the enzyme hexokinase and enters the Embden-Meyerhof pathway, providing the major aerobic energy source for the cell (Kador et al

Mi Y, Zhao J, Feng SS

Studies observed through two-photon imaging that neurons in awake mice preferentially uptake the glucose analog 2-deoxyglucose-IR (2DG-IR) during sensory stimulation, with higher hexokinase expression than astrocytes, indicating that neurons have an intrinsic ability to metabolize glucose through enhanced glycolysis (Tang, 2018