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In this process, 10 L of the ITC was mixed with 25 mg of lysine in 10 mL of water:ethanol (1:1, pH = 10) at room temperature for 24 h

That unexpected result drove us to test lower concentrations in a dose-response manner

However, this pathway is reported to be inactive in most tissues, and in the few tissues in which it is active, its function is reduced in tumours from the corresponding tissue 16