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The NAD+/NADH ratio typically ranges from 3:1 to 10:1 in healthy cells, with this ratio serving as an indicator of cellular energy status and metabolic activity

However, uncontrolled autophagy can also cause cell death, which is referred to as autophagy-dependent cell death [6]

Fut Oncol 14:927936 Zhang Y, Shi J, Liu X, Feng L, Gong Z, Koppula P, Sirohi K, Li X, Wei Y, Lee H et al (2018b) BAP1 links metabolic regulation of ferroptosis to tumour suppression