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This is something I recognise and If that is the chosen path, I will do my best to ensure anyone who chooses this route is supported and all steps I can do are made to prioritise their health

Abraham JE, Svare CW, Frank CW

Additionally, there is evidence indicating that enhanced pro-inflammatory cytokine signalling may promote ROS generation and lead to oxidative damage which is schematized in ( Figure 6 )

Other factors proposed in the pathogenesis of IBD include an initial breakdown of the epithelial barrier which can lead to a self-amplifying cycle of immune activation and cytokine release [79], and loss of tolerance to endogenous microflora and dietary antigens [82,87]