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Given this situation it is particularly concerning that MDA campaigns show that PZQ cure rates are often less than 50% and modeling studies demonstrating that these campaigns with PZQ alone are unlikely to interrupt transmission, and once MDA is suspended, the prevalence of infection is likely to rebound to pre-MDA levels 9,10,11

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This regimen maintains a low pH (approximately 4.0), inhibiting the adherence of pathogens and consequently reducing the risk of preterm birth (160)

Candida auris has drawn considerable attention due to its high level of multidrug resistance, with fluconazole resistance detected in 70%-90% of isolates (Navalkele et al., 2017