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Together, our data indicate that not only the mutant or WT status of Rb but also the expression levels of FZR1 and functional activity of the APC/C FZR1 E3 ligase will determine how cancer cells respond to CDK4/6 inhibitor treatment

In stage II, the expression levels of these three genes were relatively high, suggesting they could be clinical indicators and providing a preliminary basis for later tumor heterogeneity

Mei Fong Looi, graduate student, Deans List, College of Business, Master of Science in actuarial science

The results of published studies, however, are inconsistent, and the role of coagulation factors in the development of RVO remains unclear