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This suggests LL-37 acts as an alarm system, redirecting mast cells from allergic mode to infection-fighting mode when bacteria are present

ChIP-seq and ChIP assay CUT&Tag assay was performed for chromatin immunoprecipitation/high-throughput sequencing (ChIP-seq)

Uppal A, Bhutiani N, YC Shen JP, Alfaro K, Kell RJ, Yousef MM, Yousef AM, Konishi T, Holliday E, Morris VK, Dasari A, Willis J, Newhook TE, Bednarski BK, You Y, Peacock O, Messick C, Das P, Chang GJ, Kopetz S

Conclusions GLP-1RAs provide a novel approach for treating obesity-related asthma by simultaneously targeting metabolic dysfunction and airway inflammation