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Alkynylated probes derived from senolytic chloroacetamides A detailed description of the synthesis of alkynylated probes derived from senolytic chloroacetamides and the NMR spectra of the synthesized probes is provided in Supplementary Note 1

More specifically, the researchers posited that IGF-1 LR3 cleared faster as it appeared to bind to a lower degree to binding proteins than endogenous IGF-1