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They had three control groups one received treatment with curcumin, one with a non-steroidal anti-inflammatory drug (NSAID) called diclofenac, and a third with a combination of the two

& Sanyal, A

10.1080/10611860903055470 105 MobarraN.ShanakiM.EhteramH.NasiriH.SahmaniM.SaeidiM.et al (2016)

In fact, the GLP- 1 receptor-cAMP-PKA axis stimulates the growth of beta cells by activating the transducer of regulated cAMP response element-binding protein (CREB) (TORC2) and the expression of the CREB and insulin receptor substrate 2 genes [57] Additionally, by boosting bcl- 2 activity and blocking the proapoptotic Bax, activated CREB also supports beta cell survival [58]