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doi: 10.1038/s42003-025-08424-x 160

For others, it can take longer, especially if symptoms have been present for months or if there are multiple contributing factors (iron, vitamin D, thyroid issues, sleep, stress, etc.)

+ - It is important to acknowledge that many anonymous online users of BPC-157 report adverse effects, including injection site pain and swelling, joint pain, anxiety, panic attacks, heart palpitations, insomnia, drowsiness, weakness, fatigue, loss of appetite, depression, and anhedonia

54 However, previous studies have also demonstrated that MSCs are capable of secreting anti-inflammatory cytokines, anticatabolic mediators, and growth factors when cultured under IDD-like conditions both in vitro 55 and ex vivo, 56 hence demonstrating an immunomodulatory effect on resident IVD cells