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3 Mechanism of AS-IV in arrhythmia The underlying pathological mechanisms of arrhythmia include ischemia-reperfusion injury, fibrosis, and ion channel dysfunction, all of which disrupt the normal electrical conduction and automaticity of the heart

This leads to Pink1 accumulation on the OMM, which promotes the recruitment of the E3 ligase Parkin to mitochondria [275, 276]

Enzymatic Subcision and Remodeling (ESR) describes the mechanism of action of Qwoinjections